Nausea and Vomiting

Authored by , Reviewed by Dr Laurence Knott on | Certified by The Information Standard

Nausea is the feeling of wanting to be sick (vomit). Vomiting is when you are sick, or 'throw up'. The contents of your stomach rise up your food pipe (gullet, or oesophagus) and spill out of your mouth or nose. Nausea and vomiting are controlled by a combination of the vomiting centre in your brain, and areas within your gut.

Nausea and vomiting may be due to many different causes. Common causes include food poisoning, a tummy bug (viral infection), drinking a lot of alcohol, and being pregnant. You should get medical advice if you vomit repeatedly for more than 48 hours or feel unwell or weak. If you vomit blood or have unexplained problems like weight loss or difficulty swallowing, you should see your GP urgently. The most common causes are mentioned below.

The doctor will want to know how long your feeling sick and being sick (nausea and vomiting) have lasted and whether you have any other symptoms. The doctor will particularly ask about symptoms which may suggest an underlying serious condition. These are known as 'red flags'. The sort of information your doctor will want to know includes the following:

  • Did it start suddenly or develop over time? Did anything trigger it? How long has it lasted?
  • When do you vomit? Is it worse when you move your head?
  • Do you feel feverish?
  • Are you coughing up blood or bile?
  • Do you feel ill? Do you have a high temperature (fever), weight loss or tummy (abdominal) pains? Do you have headaches?
  • How much alcohol do you drink?
  • When was your last period? Could you be pregnant?
  • Have you started any new medication recently?

This information will help the doctor to work out the cause of your nausea and/or vomiting. Your doctor will examine you. He or she will check your temperature, chest and abdomen. You may be asked to produce a urine sample and have a blood test. You may be asked to do a pregnancy test. Further tests of your stomach and abdomen may be advised. Referral to a specialist is possible.

  • Avoid a lack of fluid in your body (dehydration): drink little and often to replace any fluid you have lost. Consider using rehydration drinks, such as Dioralyte®.
  • Call 999/112/911 if being sick (vomiting) is severe and you are weak or have severe tummy (abdominal) pain.
  • See your doctor urgently (within a few days) if you develop 'red flag' symptoms.
  • See your doctor if your vomiting lasts for more than 48 hours and is not improving.

The following features may indicate serious underlying disease:

There are many causes of feeling sick and being sick (nausea and vomiting). The following is a list of some of the most common or important causes. See the links for more information about each condition.

  • Metabolic conditions - for example:
    • Diabetes, particularly if poorly controlled. Diabetic ketoacidosis (when breakdown products called ketones circulate in the blood) occurs most commonly on patients who are on insulin, and is usually caused by being unwell and not using enough insulin. It can cause persisting, increasing vomiting.
    • Addison's disease. This rare condition develops over several months and also causes severe fatigue, weight loss, low blood pressure and other symptoms.
    • Hypercalcaemia. A high calcium level is most commonly due to parathyroid gland overactivity, but it can also be caused by certain cancers.

Other causes

Appendicitis, inflammation of the pancreas (pancreatitis), kidney stones, stomach ulcers and gallstones can all cause severe tummy (abdominal) pain and nausea and vomiting. If severe, ring 999/112/911 to call for an ambulance.

Blockage (obstruction) of the gut - repeated and severe vomiting may be due to a blockage anywhere along the gut (intestine). This could be a twisted loop of bowel, cancerous growth or non-cancerous narrowing. This will usually be associated with severe tummy pain. Because there is a blockage, usually you would be unable to open your bowels. This is an emergency and you need to call an ambulance.

Raised pressure in the brain - meningitis, brain tumours and head injuries can increase pressure in the brain, which can cause nausea and vomiting. Ring 999/112/911 to call for an ambulance if you suspect your child has meningitis.

Liver disease - for example, hepatitis Ahepatitis Bliver cirrhosis. There will be other symptoms, including yellowing of the skin and of the whites of the eyes (jaundice) and, usually, pain over the liver.

Kidney problems - for example, chronic kidney disease, which typically causes nausea when severe, and kidney stones (which may also cause pain).

Acute nausea and/or vomiting usually mean lasting less than 24-48 hours. They are most commonly due to gastric infection or food poisoning and are self-limiting (ie each stops by itself). This sort of nausea and vomiting does not usually need any intervention unless it is very severe, the vomit is unusual (for example, bloody) or the person affected is a baby or young child and not managing fluids, or if lack of fluid in the body (dehydration) is a problem.

Persistent nausea and vomiting is that which lasts for 48 hours or more. It can have the same causes as acute nausea and vomiting, but simple infections and food poisoning start to look less likely as time goes on, and other possible causes come to the fore. Some are more serious than others, and many cause other symptoms too. 

Persistent nausea, which is that experienced in pregnancy, on a long sea voyage, when taking chemotherapy, or due to a chronic medical condition, can be very distressing. Severe nausea can be exhausting and depressing, and some people think it is worse than vomiting (which can feel like a relief to people with persistent nausea).

  • Repeated vomiting can cause dehydration, particularly in babies and small children.
  • Persistent vomiting leads to loss of water and salts from the body, including sodium, potassium and chloride. Altering the balance of the body's salts can lead to complications, including irregularities of the heart rhythm. It can be very difficult to replace lost fluids and salts whilst vomiting continues.
  • Tooth enamel damage is common in people with bulimia nervosa who induce vomiting on a regular basis as part of their illness. The acid from the stomach erodes and damages teeth, and digestive enzymes damage gums, leading to dental complications.
  • Tears of the oesophageal lining (Mallory-Weiss tears) can cause bleeding, and you may see blood in the vomit. Recurrent vomiting can also lead the stomach and gullet to become inflamed (gastritis and oesophagitis).
  • Vomiting whilst unconscious (for instance, after excess alcohol) can be very dangerous, as it can lead to stomach contents getting into your windpipe, and therefore into your lungs, where it can obstruct breathing or lead to severe lung inflammation.

Further reading and references

  • ; NICE CKS, June 2013 (UK access only)

  • ; NICE CKS, July 2015 (UK access only)

  • ; NICE Clinical Guideline (April 2009)

  • ; Public Health England (March 2012)

  • ; Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev. 2015 Sep 89:CD007575.

  • ; NICE CKS, July 2015 (UK access only)

  • ; Scopolamine (hyoscine) for preventing and treating motion sickness. Cochrane Database Syst Rev. 2011 Jun 15(6):CD002851.

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